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DFG Research Unit FOR2722


Novel molecular determinants for musculoskeletal extracellular matrix homeostasis - a systemic approach


At a glance



New publication by project M1

Bent Brachvogel's group identifies the mitochondrial respiratory chain as a new therapeutic target for treating a defective extracellular matrix in degenerative cartilage disease:
Dysfunction in the mitochondrial respiration leads to cartilage degenerative diseases

Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage


Interview with Honorary Doctor Mats Paulsson

Please visit University of Oulu's official Spotify channel


New publication by project D1

The research unit FOR2722 congratulates Prof. Brunhilde Wirth for her outstanding detective work in science.

VWA1 identified as a new disease gene for neuromyopathy: An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy


New publication by project B1

Novel structure-function relationships of myopathy patient mutations in collagen VI identified by Mats Paulsson and Raimund Wagner of the Research Unit. Results shed light on possible myopathy mechanisms.



The University of Oulu will confer an honorary doctorate to FOR2722 member Prof. Mats Paulsson

The research unit FOR2722 congratulates Prof. Mats Paulsson for receiving the honorary degree of the University of Oulu.

To acknowledge his longtime commitment and outstanding research on extracellular matrix the Faculty of Biochemistry and Molecular Medicine will confer Prof. Paulsson the highest honor granted by the University of Oulu.


New publication by project B1:

FOR 2722 researchers resolve the in vivo biogenesis of endotrophin, a proteolytic fragment of collagen VI that has been proposed to act as an adipokine.

This article has been recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Peter Torzilli.


FOR2722 member Prof Dr. Brunhilde Wirth receives the NRW-Innovation prize 2019

The state government of North Rhine-Westphalia awarded the NRW-Innovation prize 2019 to Prof. Dr. Brunhilde Wirth for her groundbreaking research on spinal muscular dystrophy.

The research unit FOR2722 congratulates Prof. Dr. Brunhilde Wirth and wishes her every success for her future research.