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2020

Auler A, Bergmeier V, Georgieva VS, Pitzler L, Frie C, Nüchel J, Eckes B, Hinz B, Brachvogel B 2020 miR-127-3p is an epigenetic activator of myofibroblast senescence situated within the miRNA enriched Dlk1-Dio3 imprinted domain on mouse chromosome 12.  J Invest Dermatol. [Epub ahead of print]

 

Etich J, Leßmeier L, Rehberg M, Sill H, Zaucke F, Netzer C, Semler O 2020 Osteogenesis imperfecta-pathophysiology and therapeutic options. Mol Cell Pediatr. 7(1):9.

Etich J, Rehberg M, Eckes BSengle GSemler OZaucke F 2020 Signaling pathways affected by mutations causing osteogenesis imperfecta. Cell Signal. [Epub ahead of print]

Georgieva VS, Etich J, Bluhm B, Zhu M, Frie C, Wilson R, Zaucke F, Bateman J, Brachvogel B 2020 Ablation of the miRNA Cluster 24 Has Profound Effects on Extracellular Matrix Protein Abundance in Cartilage. Int J Mol Sci 21(11):E4112.

Godmann L, Bollmann M, Korb-Pap A, König U, Sherwood J, Beckmann D, Mühlenberg K, Echtermeyer F, Whiteford J, De Rossi G, Pap T, Bertrand J 2020 Antibody-mediated inhibition of syndecan-4 dimerisation reduces interleukin (IL)-1 receptor trafficking and signalling. Ann Rheum Dis. 79(4):481-489.

Hedderich J, El Bagdadi K, Angele P, Grässel S, Meurer A, Straub RH, Zaucke F, Jenei-Lanzl Z 2020 Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation. Int J Mol Sci 21(11):E3924.

Heilig J, Dietmar H, Brachvogel BPaulsson MZaucke FNiehoff A 2020 Collagen IX deficiency causes premature vascularization and ossification of murine femoral heads through an imbalance of pro- and antiangiogenic factors. Osteoarthritis Cartilage 28(7):988-999.

Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combémorel N, Riemenschneider C, Allègre N, Zhang J, Wajda P, Rama N, Vieugué P, Durand I, Brevet M, Gadot N, Imhof T, Merrill BJ, Koch M, Mehlen P, Chazaud C, Meissner A, Lavial F 2020 Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signaling. Nat Cell Biol 22(4):389-400.

Köhler A, Mörgelin M, Gebauer JM, Öcal S, Imhof T, Koch M, Nagata K, Paulsson M, Aumailley M, Baumann U, Zaucke FSengle G. 2020 New specific HSP47 functions in collagen subfamily chaperoning. FASEB J. 34(9):12040-12052.

Li P, Fleischhauer L, Nicolae C, Prein C, Farkas Z, Saller MM, Prall WC, Wagener R, Heilig J, Niehoff A, Clausen-Schaumann H, Alberton P, Aszodi A 2020 Mice lacking the matrilin family of extracellular matrix proteins develop mild skeletal abnormalities and are susceptible to age-associated osteoarthritis. Int J Mol Sci 21(2).

Rehberg M, Azim M, Martakis K, Winzenrieth R, Hoyer-Kuhn H, Schoenau E, Semler O, Duran I 2020 Bone microarchitecture assessed by trabecular bone score is independent of mobility level or height in pediatric patients with cerebral palsy. J Bone Miner Res. [Epub ahead of print]

Solomon-Degefa H, Gebauer JM, Jeffries CM, Bird LE, Baumann U, Svergun DI, Owens RJ, Werner JM, Paulsson MWagener R 2020 Structure and flexibility of the collagen VI α3 chain VWA domain array: Functional implications of myopathy causing mutations. J Biol Chem. 295(36):12755-12771.

van Dijk FS, Semler O, Etich J, Köhler A, Jimenez-Estrada JA, Bravenboer N, Claeys L, Riesebos E, Gegic S, Piersma SR, Jimenez CR, Waisfisz Q, Flores CL, Nevado J, Harsevoort AJ, Janus GJM, Franken AAM, van der Sar AM, Meijers-Heijboer H, Heath KE, Lapunzina P, Nikkels PGJ, Santen GWE, Nüchel J, Plomann M, Wagener R, Rehberg M, Hoyer-Kuhn H, Eekhoff EMW, Pals G, Mörgelin M, Newstead S, Wilson BT, Ruiz-Perez VL, Maugeri A, Netzer C, Zaucke F, Micha D. 2020 Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2. Am J Hum Genet. 107(5):989-999.

Westermann LM, Fleischhauer L, Vogel J, Jenei-Lanzl Z, Ludwig NF, Schau L, Morellini F, Baranowsky A, Yorgan TA, Di Lorenzo G, Schweizer M, de Souza Pinheiro B, Guarany NR, Sperb-Ludwig F, Visioli F, Oliveira Silva T, Soul J, Hendrickx G, Wiegert JS, Schwartz IVD, Clausen-Schaumann H, Zaucke F, Schinke T, Pohl S, Danyukova T. 2020 Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma. Dis Model Mech. 13(11).

Wirth B, Karakaya M, Kye MJ, Mendoza-Ferreira N 2020 Twenty-five years of spinal muscular atrophy research: from phenotype to genotype to therapy, and what comes next. Annu Rev Genomics Hum Genet [Epub ahead of print]